Objective: Teacher-student Interaction is the basis of education and one of the important elements of classroom management, and the interactive relationship can only be imagined between "agents". The purpose of this research was to design the optimal model of Teacher-student Interaction based on Teacher agency from the perspective of the Islamic approach (human as an agent). In this approach, human personality is mainly built through his action and agency, and his agency is based on basic cognitive, tendency and volitional principles. The Interaction based on the mentioned approach will be an asymmetric Interaction due to the difference in the level between the three principles of cognitive, tendency and volition between the Teacher and the student.Materials and methods: The current research method is qualitative and the research data was collected using semi-structured interviews with 17 experts in the field of philosophy of education, psychology and lesson planning who were familiar and proficient in the field of agency and and were selected using a theoretical sampling method were collected. Data analysis was done by thematic analysis technique of thematic network type. Using the 6-step method of Brown and Clark (2006), the concepts extracted from the data in the classes of primary codes (concepts), sub-themes (sub-themes) and main themes were analyzed by maxqda software and a schematic map was drawn from the data. Also, the validity of the findings was confirmed through the methods of triangulation in the method (re-examination of work methods) and triangulation in the researcher (reliability test between coders).Discussion and conclusion: The findings of the research showed that the desired model of Teacher-student Interaction based on agency consists of four main themes including cognitive, emotional, voluntary and behavioral, personality/identity/secretary. The cognitive or epistemological content includes the components of high-level thinking, scientific and rational validity, the position and role of the Teacher, and logical flexibility; emotional theme or tendency with components of acceptance and positive attitude, kindness (intimacy) and empathy; Voluntary and behavioral content including the components of decision on change of mind, cooperation and dialogue-oriented, the power to arouse the will of others, the content and manner of speech, acting on knowledge and desirable behaviors; And finally, the theme of personality/identity/secretary includes the components of personality stability and desirable qualities and temperament of the Teacher. The results of the present research showed that the asymmetric Interaction between Teacher and student based on agency - far from the two poles of Teacher-centered and student-centered - and by recognizing and welcoming the basics of Teacher and student agency, can be formulated in the sense that education and upbringing based on The approach of "man as an agent" is not Teacher-centered and will seek to shape and transfer knowledge to the student, nor is it student-centered that the Teacher is left aside only as a guide on the sidelines. Rather, a Teacher who conforms to this approach is rich and fruitful in cultural heritage (knowledge and human values) and plans and implements the process of education and upbringing at least by recognizing and at least by welcoming the triple principles of students' agency, and in all The mentioned steps always criticize and re-evaluate their actions by themselves and the students. It is suggested that the emphatic issue of authorized and unauthorized authority in the approach of "man as an agent" should be at the forefront of Teachers' professional activities, and dear Teachers should equip themselves as much as possible in the field of authorized content authority (knowledge, values and skills). and allow formal authority only in the shadow of content authority and with the collaborative formulation of classroom regulations and avoid any formal authority seeking that weakens or eliminates students' agency and one-sided Interaction. In fact, tending to content authoritarianism and avoiding formal authoritarianism is considered one of the necessities of the teaching profession.